A pioneering surgical procedure, known as agonist-antagonist myoneural interface (AMI), allows amputees to control bionic limbs via their nervous system, enabling natural gait and spatial awareness. A study published in Nature Medicine demonstrated success in seven patients with bionic legs. About 60 people globally have undergone this procedure, which can be applied to both legs and arms. This technique marks the first instance of a prosthesis under full neural modulation, where the human nervous system, not a robotic algorithm, controls movement.